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STEMCELL Technologies Human Recombinant MCP-1 (CCL2)
Monocyte chemotactic protein 1
Brand: STEMCELL Technologies 78087
Additional Details : Weight : 0.00110kg
Description
- Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, is a member of the CC family of chemokines
- The protein is primarily induced by platelet-derived growth factor (PDGF) gene (Cochran et al.) The biological effects of MCP-1 are mediated via the specific G-protein-coupled receptor CCR2 which in turn activates signal transduction pathways leading to monocyte transmigration
- Migration of monocytes from the bloodstream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as other immunomodulatory effects
- MCP-1 is produced by a variety of cell types, including fibroblasts and endothelial, epithelial, smooth muscle, mesangial, astrocytic, monocytic, and microglial cells, which are important for antiviral responses in the peripheral circulations and in tissues
Specifications
| DIA, Differentiation-inducing factor, HILDA, Human interleukin in DA cells, Leukemia inhibitory factor, MCAF, Melanoma-derived LPL inhibitor, MLPLI, Monocyte chemoattractant protein 1 | |
| 5 μg | |
| Macrophages; Monocytes; Myeloid Cells; NK Cells; T Cells | |
| ≥95% |