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STEMCELL Technologies Human Recombinant MCP-1 (CCL2)

Product Code. 17109541
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Quantity:
20 μg
5 μg
Unit Size:
20µg
5µg
This item is not returnable. View return policy

Product Code. 17109541

Brand: STEMCELL Technologies 78087

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This item is not returnable. View return policy

Description

Monocyte chemotactic protein 1

  • Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, is a member of the CC family of chemokines
  • The protein is primarily induced by platelet-derived growth factor (PDGF) gene (Cochran et al.) The biological effects of MCP-1 are mediated via the specific G-protein-coupled receptor CCR2 which in turn activates signal transduction pathways leading to monocyte transmigration
  • Migration of monocytes from the bloodstream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as other immunomodulatory effects
  • MCP-1 is produced by a variety of cell types, including fibroblasts and endothelial, epithelial, smooth muscle, mesangial, astrocytic, monocytic, and microglial cells, which are important for antiviral responses in the peripheral circulations and in tissues

Specifications

Name DIA, Differentiation-inducing factor, HILDA, Human interleukin in DA cells, Leukemia inhibitory factor, MCAF, Melanoma-derived LPL inhibitor, MLPLI, Monocyte chemoattractant protein 1
Quantity 5 μg
Cell Type Macrophages; Monocytes; Myeloid Cells; NK Cells; T Cells
Purity or Quality Grade ≥95%
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