missing translation for 'onlineSavingsMsg'
Learn More
Learn More
STEMCELL Technologies Human Recombinant IL-7, ACF
Interleukin 7, animal component-free
Brand: STEMCELL Technologies 78196
Additional Details : Weight : 0.00110kg
Description
- Interleukin 7 (IL-7) is a member of the type I cytokine family that is critical for T and B cell development and survival
- It is produced by non-hematopoietic cells in the thymus, lymphoid organs, and by bone marrow stromal cells (Lundström et al.) IL-7 binds to a receptor (IL-7R) composed of common gamma chain and IL-7Ra (CD127) and signals through the JAK/STAT and PI3K pathways
- IL-7 regulates the survival of naïve and memory CD4+ and CD8+ T cells, γδ T cells, NK T cells, innate lymphoid cells, and regulatory T cells (Carrette & Surh)
- Although a deficiency in IL-7R still permits the generation of normal numbers of peripheral B cells in humans, stimulation of human B cell precursors with IL-7 could promote STAT5-dependent proliferation and survival in vitro (Clark et al.; Corfe & Paige)
- This product is animal component-free
Specifications
| Interleukin-7, LP-1, Lymphopoietin 1, Pre-B cell factor | |
| 10 μg | |
| Hematopoietic Stem and Progenitor Cells | |
| ≥95% |