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Invitrogen™ Human PRRT2 (aa 15-116) Control Fragment Recombinant Protein

Product Code. 30201796
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30201796

Brand: Invitrogen™ RP108864

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q7Z6L0
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 112476
Name Human PRRT2 (aa 15-116) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1500031I19Rik; AI195361; BFIC2; BFIS2; Dispanin subfamily B member 3; DSPB3; dystonia 10; DYT10; EKD1; FICCA; ICCA; IFITMD1; infantile convulsions and paroxysmal choreoathetosis; interferon induced transmembrane protein domain containing 1; PKC; proline rich transmembrane protein 2; proline-rich transmembrane protein 2; PRRT2; RGD1564195
Common Name PRRT2
Gene Symbol PRRT2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence EESPKVPGEGPGHSEAETGPPQVLAGVPDQPEAPQPGPNTTAAPVDSGPKAGLAPETTETPAGASETAQATDLSLSPGGESKANCSPEDPCQETVSKPEVSK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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