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Invitrogen™ Human PPAPDC1B Synthetic Peptide

Product Code. 15369250
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Quantity:
50 μg
Unit Size:
50µg
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15369250 50 μg 50µg
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Product Code. 15369250 Supplier Invitrogen™ Supplier No. PEP0995

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Description

Synthetic Peptide

PPAPDC1B Synthetic Peptide, PEP-0995, from Invitrogen.

Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 84513
Species Human
Purification Method purified
Accession Number Q8NEB5
Common Name Human PPAPDC1B
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol PLPP5
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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