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Invitrogen™ Human PHAP Synthetic Peptide

Product Code. 15266369
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Quantity:
50 μg
Unit Size:
50µg
Product Code. Quantity unitSize
15266369 50 μg 50µg
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Product Code. 15266369

Brand: Invitrogen™ PEP0145

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This item is not returnable. View return policy

Description

Synthetic Peptide

PHAP Synthetic Peptide, PEP-0145, from Invitrogen.

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 8125
Species Human
Purification Method purified
Accession Number P39687
Common Name Human PHAP
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol ANP32A
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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