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Invitrogen™ Human Laminin alpha-2 (aa 2111-2242) Control Fragment Recombinant Protein

Product Code. 30202074
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30202074

Brand: Invitrogen™ RP108166

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P24043
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 3908
Name Human Laminin alpha-2 (aa 2111-2242) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 5830440B04; dy; dystrophia muscularis; Lama2; laminin alpha-2; laminin M; Laminin M chain; laminin subunit alpha 2; laminin subunit alpha-2; laminin, alpha 2; laminin-12 subunit alpha; Laminin-2 subunit alpha; laminin-4 subunit alpha; LAMM; mer; merosin; Merosin heavy chain; mKIAA4087
Common Name Laminin alpha-2
Gene Symbol Lama2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGT
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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