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Invitrogen™ Human IL-31, AOF Recombinant Protein
E. coli Recombinant Protein
3325.00 NOK - 73400.00 NOK
Specifications
| Accession Number | Q6EBC2 |
|---|---|
| For Use With (Application) | Control, ELISA, Functional Assay, Western Blot |
| Formulation | 20 mM sodium phosphate with 50 mM NaCl and no preservative |
| Gene ID (Entrez) | 386653 |
| Molecular Weight (g/mol) | 15.8 kDa |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17616535
|
Invitrogen™
RP87713 |
100 μg |
11420.00 NOK
100µg |
Estimated Shipment: 24-05-2024 Log in to see stock. |
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|
17626535
|
Invitrogen™
RP87715 |
1 mg |
73400.00 NOK
1mg |
Estimated Shipment: 24-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
17636535
|
Invitrogen™
RP87716 |
25 μg |
3325.00 NOK
25µg |
Estimated Shipment: 24-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
17646535
|
Invitrogen™
RP87717 |
500 μg |
45850.00 NOK
500µg |
Estimated Shipment: 24-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.- Purity: >95% by SDS-Page
- Endotoxin Concentration: AX41 ≤EUs/μg
- Protein Length: 141 aa.
- Biological Activity: <25 ng/mL
- Molecular Weight: 15.8 kDa
- Animal Origin Free: Yes
Specifications
| Q6EBC2 | |
| 20 mM sodium phosphate with 50 mM NaCl and no preservative | |
| 15.8 kDa | |
| E. coli | |
| RUO | |
| Il31 | |
| Unconjugated | |
| Lyophilized |
| Control, ELISA, Functional Assay, Western Blot | |
| 386653 | |
| Human IL-31, AOF | |
| -20°C | |
| 1700013B14Rik; Il31; IL-31; ILN; Interleukin; interleukin 31; Interleukin-31 | |
| Human | |
| Recombinant | |
| >95% |