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  4. Gibco™ Human IL-3 Recombinant Protein

Gibco™ Human IL-3 Recombinant Protein

Product Code. 10223263
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Quantity:
1 mg
10 μg
100 μg
50 μg
Unit Size:
100µg
10µg
1mg
50µg
Product Code. Quantity unitSize
10223263 10 μg 10µg
10573785 100 μg 100µg
10314033 1 mg 1mg
10494953 50 μg 50µg
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Product Code. 10223263

Brand: Gibco™ PHC0034

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This item is not returnable. View return policy

Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized recombinant human IL-3 in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20°C. Further dilution should be made in medium or buffered solution containing carrier protein, such as PBS with 0.1% BSA. Storage: Lyophilized recombinant human IL-3 should be stored at 2°C to 8°C, preferably desiccated. Store reconstituted recombinant human IL-3 at ≤-20°C (not in a frost-free freezer). Keep freeze-thaw cycles to a minimum.

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P08700
For Use With (Application) Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 3562
Molecular Weight (g/mol) 15 kDa
Name Human IL-3
Purification Method Purified
Quantity 10 μg
Storage Requirements 4°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF
Common Name IL-3
Gene Symbol IL3
Biological Activity ED50 = 0.1 - 0.25 ng/mL; determined by the dose-dependent proliferation of human TF-1 cells.
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Sequence APMTQTTPLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
Content And Storage 4°C
Classification Carrier-Free
Activity ED50 = 0.1 - 0.25 ng/mL; determined by the dose-dependent proliferation of human TF-1 cells.
Endotoxin Level <0.1 ng/μg
Shipping Condition Wet Ice
Expression System E. coli
Protein Family Cytokines & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype Interleukins
Research Category Stem Cell Research, Immunology
Product Line Gibco
Purity or Quality Grade >95% by SDS-PAGE
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