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Gibco™ Human IL-3, Animal-Free Recombinant Protein, PeproTech®
Description
Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Specifications
Specifications
| Accession Number | P08700 |
| For Use With (Application) | Functional Assay |
| Format | Lyophilized |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 3562 |
| Molecular Weight (g/mol) | 15 kDa |
| Name | Human IL-3, Animal-Free |
| Purification Method | HPLC, SDS-PAGE |
| Quantity | 2 μg |
| Regulatory Status | RUO |
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