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Invitrogen™ Human IL-1 beta, Recombinant Protein
E. coli Recombinant Protein
Brand: Invitrogen™ A42521
Additional Details : Weight : 0.02180kg
Description
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.Specifications
| P05362 | |
| protein with 0.02% Tween 80, 140 mM NaCl, 2.7 mM KCl, 5% mannitol, 5% trehalose and no preservative | |
| Human ICAM-1 (CD54) Fc Chimera | |
| HEK293 cells | |
| RUO | |
| BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; intercellular adhesion molecule-like; LOC100345640; Ly-47; Major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54 | |
| Human | |
| Recombinant | |
| ≥ 90% |
| Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot | |
| 3383 | |
| 5 x 5 μg | |
| -20°C | |
| <1 EU/μg | |
| ICAM1 | |
| Unconjugated | |
| Lyophilized |