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ACROBiosystems Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag

SPR & BLI verified

Brand:  ACROBiosystems FCN-H52W7-50ug

Additional Details : Weight : 0.00010kg

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Product Code. 16447529

  • 4432.75 NOK / 50µg
Estimated Shipment: 16-01-2023
to see stock.

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Description

Description

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 32.3 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunit Beta-2
Specifications

Specifications

NP_001129491.1 (FCGRT) and NP_004039.1 (B2M)
32.3 kDa (FCGRT) and 11.7 kDa (B2M)
50 µg
Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M)
FcRn,FCGRT and B2M
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human FCGRT&B2M; Heterodimer Protein, His Tag (SPR and BLI verified) (FCN-H52W7) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) and P61769-1 (B2M)).
-20°C
FcRn (FCGRT and B2M)
His Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Fc Receptors
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