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Gibco™ Human Eotaxin-3 (CCL26) Recombinant Protein, PeproTech®

Product Code. 17862433
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Quantity:
1 mg
100 μg
20 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
1mg
20µg
250µg
500µg
5µg
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Product Code. 17862433

Brand: Gibco™ 300481MG

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This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9Y258
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 10344
Molecular Weight (g/mol) 8.4 kDa
Name Human Eotaxin-3 (CCL26)
Quantity 1 mg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias CC chemokine IMAC; C-C motif chemokine 26; C-C motif chemokine ligand 26; Ccl26; Ccl26l; chemokine (C-C motif) ligand 26; chemokine N1; Eotaxin3; eotaxin-3; IMAC; Macrophage inflammatory protein 4-alpha; MGC126714; MIP-4 A; MIP-4 alpha; MIP-4-alpha; PRO242; SCYA26; SCYA26MIP-4-alpha; small inducible cytokine A26; small inducible cytokine subfamily A (Cys-Cys), member 26; small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; UNQ216; UNQ216/PRO242
Common Name Eotaxin 3
Gene Symbol CCL26
Biological Activity Determined by its ability to chemoattract human CCR3/HEK293 cells. The maximum activity was achieved (at 2 ug/ml)
Conjugate Unconjugated
Recombinant Recombinant
Sequence TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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