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ACROBiosystems Human Complement Factor D / CFD Protein, His Tag (active enzyme)

Brand:  ACROBiosystems CFD-H52H8-50ug

Additional Details : Weight : 0.00010kg

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Product Code. 16447419

  • 4432.75 NOK / 50µg
Estimated Shipment: 20-01-2023
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Description

Description

Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 28 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_001919.2
26.3 kDa
50 µg
Ile 26 - Ala 253
CFD,Adipsin,PFD,DF,Complement factor D
Unconjugated
50 mM Tris, 150 mM NaCl, pH8.0
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human Complement Factor D, His Tag (CFD-H52H8) is expressed from human 293 cells (HEK293) and active. It contains AA Ile 26 - Ala 253 (Accession # P00746-1).
-20°C
Complement Factor D
His Tag
Less than 1.0 EU / µg by the LAL method.
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