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Invitrogen™ Human CCL3 (MIP-1 alpha) Recombinant Protein

Product Code. 11588971
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Quantity:
1 mg
Unit Size:
1mg
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Product Code. 11588971

Brand: Invitrogen™ RP75652

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This item is not returnable. View return policy

Description

Recombinant Protein

This product contains purified recombinant human MIP-1a protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P10147
Concentration 0.10 mg/mL
For Use With (Application) Control, Western Blot
Formulation 20 mM tris HCl with 50% glycerol and no preservative; pH 8
Gene ID (Entrez) 6348
Name Human CCL3 (MIP-1 alpha)
Quantity 1 mg
Source E. Coli
Regulatory Status RUO
Gene Alias AI323804; C-C motif chemokine 3; C-C motif chemokine ligand 3; CCL3; chemokine (C-C motif) ligand 3; G0/G1 switch regulatory protein 19-1; G0S19-1; Heparin-binding chemotaxis protein; H-MIP-1-alpha; L2G25B; LD78ALPHA; LD78-alpha; LD78-alpha(4-69); Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3); macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1 alpha; MIP1 (a); mip1 alpha; MIP-1 alpha; MIP1-(a); MIP1A; MIP-1 A; MIP-1 alpha; MIP-1-alpha; MIP1-alpha; MIP-1-alpha(4-69); PAT 464.1; RP23-320E6.7; Scya3; SIS-alpha; SIS-beta; small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1 A); small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; TY-5
Common Name CCL3 (MIP-1 alpha)
Gene Symbol CCL3
Conjugate Unconjugated
Species E. coli
Recombinant Recombinant
Protein Tag His-tag
Sequence Amino acids Ala27-Ala92 containing an N-terminal His-tag
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Protein Subtype Recombinant
Purity or Quality Grade >95%, by SDS-PAGE under reducing conditions
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