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ACROBiosystems Human B7-H3 (4Ig) / B7-H3b Protein, Fc Tag

Brand:  ACROBiosystems B7B-H5258-100ug

Additional Details : Weight : 0.00010kg

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Product Code. 16447199

  • 3799.50 NOK / 100µg
Estimated Shipment: 20-01-2023
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Description

Description

Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‐like and Ig C‐like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‐type and one C‐type) and shows a ubiquituous expression pattern.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.1 kDa. The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_001019907.1
73.1 kDa
100 µg
Gly 27 - Thr 461
4 Ig-B7-H3,B7-H3,CD276,PSEC0249,UNQ309/PRO352,B7 homolog 3
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by reduced SDS-PAGE
Human B7-H3 (4 Ig), Fc Tag (B7B-H5258) is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1).
-20°C
B7-H3 (4 Ig)
Fc Tag
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
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