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ACROBiosystems Human B7-H3 (4Ig) / B7-H3b Protein, Fc Tag
Brand: ACROBiosystems B7B-H5258-100ug
Additional Details : Weight : 0.00010kg
Description
Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‐like and Ig C‐like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‐type and one C‐type) and shows a ubiquituous expression pattern.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.1 kDa. The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_001019907.1 | |
| 100 μg | |
| Gly 27 - Thr 461 | |
| 4 Ig-B7-H3,B7-H3,CD276,PSEC0249,UNQ309/PRO352,B7 homolog 3 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by reduced SDS-PAGE |
| 73.1 kDa | |
| Human B7-H3 (4 Ig), Fc Tag (B7B-H5258) is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1). | |
| -20°C | |
| B7-H3 (4 Ig) | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |