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HTR1B Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 22189-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891715

  • 1281.92 NOK / 20µL
Estimated Shipment: 13-12-2022
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Description

Description

Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. In situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei.
Specifications

Specifications

HTR1B
Polyclonal
Unconjugated
HTR1B
5 HT 1B, 5 HT 1D beta, 5 HT1B, 5 HT1DB, HTR1B, HTR1D2, HTR1DB, S12, Serotonin 1D beta receptor, Serotonin receptor 1B
Rabbit
Antigen Affinity Chromatography
RUO
3351
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.51 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P28222
HTR1B
HTR1B Fusion Protein Ag16753
20 μL
Primary
Human
Antibody
IgG
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