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HPa1 Monoclonal Antibody (HP3/17), Invitrogen™

Product Code. 11554693
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Quantity:
100 μg
Unit Size:
100µg
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11554693 100 μg 100µg
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Product Code. 11554693 Supplier Invitrogen Supplier No. MA183806

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Description

Mouse Monoclonal Antibody

Purity is ∽98% by SDS PAGE. Mouse anti Human Heparanase-1 antibody, clone HP3/17 recognizes heparanase-1, also know as HPA1, an endo-beta-D-glucuronidase that degrades heparan sulfate proteoglycans (HSPGs) in the extracellular matrix through cleavage of the heparan sulfate side chains.

Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al. ). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HPa1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone HP3/17
Concentration 3.57 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.01% thimerosal
Gene HPSE
Gene Accession No. Q6YGZ1, Q9Y251
Gene Alias Endo-glucoronidase; endoglycosidase heparanase; HEP; Heparanase; Heparanase 50 kDa subunit; Heparanase 8 kDa subunit; Heparanase-1; heparanase-like; Hpa; HPA1; HPR1; HPSE; HPSE1; HSE1
Gene Symbols HPSE
Host Species Mouse
Immunogen Polypeptide from the 50 kDa subunit of heparanase
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10855, 15442
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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