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Description
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal domit polycystic kidney disease.
Specifications
Specifications
| Antigen | HELLS |
| Applications | Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | HELLS |
| Gene Accession No. | Q60848, Q9NRZ9 |
| Gene Alias | helicase, lymphoid, HELLS, LSH, Lymphoid specific helicase, Nbla10143, PASG, SMARCA6 |
| Gene Symbols | Hells |
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Product Title
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