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  8. GTS-21 dihydrochloride, MedChemExpress

GTS-21 dihydrochloride, MedChemExpress

Product Code. 16476098
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Product Code. 16476098 Supplier Medchem Express Supplier No. HY14564A

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Description

MedChemExpress GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti‐inflammatory and cognition‐enhancing activities. GTS-21 dihydrochloride is also a α4β2 (Ki=20 nM for humanα4β2) and 5-HT3A receptor (IC50=3.1 μM) antagonist.

GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti‐inflammatory and cognition‐enhancing activities. GTS-21 dihydrochloride is also a α4β2 (Ki=20 nM for humanα4β2) and 5-HT3A receptor (IC50=3.1 μM) antagonist.

Specifications

Chemical Name or Material GTS-21 dihydrochloride
CAS 156223-05-1
Color Yellow
Purity Grade Notes Research
Molecular Formula C19H22Cl2N2O2
Quantity 10 mg
Synonym DMXB-A DMBX-anabaseine
Solubility Information H2O : 50 mg/mL (131.13 mM; Need ultrasonic) ∣DMSO : 16.5 mg/mL (43.27 mM; Need ultrasonic and warming)
SMILES COC1=CC(OC)=CC=C1/C=C2CCCN=C\2C3=CC=CN=C3.Cl[H].Cl[H]
Molecular Weight (g/mol) 381.3
Formula Weight 381.3
Percent Purity 99.65%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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