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Invitrogen™ GPX4 Polyclonal Antibody
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Product Code. 11367653
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Quantity:
100 μg
Unit Size:
100µg
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11367653 100 μg 100µg
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Product Code. 11367653 Supplier Invitrogen™ Supplier No. PA519710

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with many species based on sequence homology.

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPX4
Applications Western Blot
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.02% sodium azide; pH 7.4
Gene GPX4
Gene Accession No. O70325, P36969, P36970
Gene Alias glutathione peroxidase 4; GP-GPx4; Gpx4; gpx-4; GSHPx-4; HGNC:4556; MCSP; mtPHGPx; Phgpx; phospholipid hydroperoxidase; phospholipid hydroperoxide glutathione peroxidase; phospholipid hydroperoxide glutathione peroxidase, mitochondrial; phospholipid hydroperoxide glutathione peroxidase, nuclear; SMDS; snGPx; snPHGPx; sperm nuclei glutathione peroxidase; sperm nucleus glutathione peroxidase
Gene Symbols GPX4
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human Glutathione Peroxidase 4.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2879, 29328, 625249
Target Species Human, Mouse, Rat
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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