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Description
TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Specifications
Specifications
| Antigen | GORAB |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.31 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | GORAB |
| Gene Accession No. | B1H222, Q5T7V8, Q8BRM2 |
| Gene Alias | GO, Golgin, RAB6 interacting, GORAB, hNTKL BP1, NTKL binding protein 1, NTKL BP1, NTKLBP1, RAB6 interacting Golgin, SCY1 like 1 binding protein 1, SCYL1 binding protein 1, SCYL1 BP1, SCYL1BP1 |
| Gene Symbols | GORAB |
| Show More |
Product Title
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