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GN44028, MedChemExpress

Product Code. 16417097
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 16417097

Brand: Medchem Express HY110266

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This item is not returnable. View return policy

MedChemExpress GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1α inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of cancers.

GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1α inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of cancers.

Specifications

Chemical Name or Material GN44028
CAS 1421448-26-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C18H15N3O2
Quantity 5 mg
Solubility Information DMSO : 50 mg/mL (163.76 mM; Need ultrasonic)
SMILES C1(NC2=CC=C(OCCO3)C3=C2)=NNC4=C1CC5=CC=CC=C45
Molecular Weight (g/mol) 305.33
Formula Weight 305.33
Percent Purity 99.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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