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Tocris Bioscience™ GN 44028

Potent HIF-1α inhibitor
Brand: Tocris Bioscience™ 5655/10
This item is not returnable.
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Description
GN 44028 is a potent HIF-1α inhibitor (IC50 = 14 nM). Inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. Cytotoxic to a range of cancer cell types in vitro.Specifications
| N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine | |
| 1421448-26-1 | |
| 10 mg |
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