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Invitrogen™ GLP-1 Monoclonal Antibody (10)
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Product Code. 11524142
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Quantity:
400 μL
Unit Size:
200µL
Product Code. Quantity unitSize
11524142 400 μL 200µL
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Product Code. 11524142

Brand: Invitrogen™ ABS0331002

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Description

Mouse Monoclonal Antibody

ABS 033-10-02 detects the amidated N-terminus of GLP-1(7-37) and GLP-1(7-36) in human samples. ABS 033-10-02 has been successfully used in ELISA procedures. ABS 033-10-02 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.
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Specifications

Antigen GLP-1
Applications ELISA
Classification Monoclonal
Clone 10
Concentration 1.00 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene GCG
Gene Accession No. P01275
Gene Alias GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon like peptide 1; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; Incretin hormone; MGC138331; OXM; OXY; Oxyntomodulin; PPG; preproglucagon
Gene Symbols GCG
Host Species Mouse
Immunogen Synthetic glucagon-like peptide-1 (7-17) adsorbed into aluminum hydroxide gel.
Purification Method Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2641
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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