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Description
The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-Kappa-B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
Specifications
Specifications
| Antigen | GILZ |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.23 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | TSC22D3 |
| Gene Accession No. | Q99576, Q9EQZ1, Q9Z2S7 |
| Gene Alias | DIP, DSIP immunoreactive peptide, DSIPI, GILZ, hDIP, Protein DIP, TSC 22 like protein, TSC 22 related protein, TSC 22R, TSC22 domain family protein 3, TSC22 domain family, member 3, TSC22D3 |
| Gene Symbols | TSC22D3 |
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Product Title
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