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Gibco™ Human CCL13 (MCP-4) Recombinant Protein

Product Code. 10324213
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20 μg
Unit Size:
Each
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10324213 20 μg Each
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Product Code. 10324213 Supplier Gibco™ Supplier No. PHC1154

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Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute this protein in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in tissue culture grade buffered solutions with heat inactivated fetal calf serum or low endotoxin BSA. Storage: Store lyophilized at ≤+4°C, preferably desiccated. Store reconstituted MCP-4 at -20°C in working aliquots. Avoid repeated freeze-thaw cycles.

Monocyte Chemotactic Protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as IL-1 and TNFalpha. MCP-4 is a ligand for three different G protein coupled receptors, CCR2, CCR3 and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils and basophils and this signaling is associated with the allergic response.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q99616
For Use With (Application) Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 6357
Molecular Weight (g/mol) 8.6 kDa
Name Human CCL13 (MCP-4)
Purification Method Purified
Quantity 20 μg
Storage Requirements 4°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias C-C motif chemokine 13; C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain; C-C motif chemokine ligand 13; CCL 13; CCL13; chemokine (C-C motif) ligand 13; CKb10; CK-beta-10; H-MCP-4; MCP4; MCP-4; Monocyte chemoattractant protein 4; monocyte chemotactic protein 4; NCC1; NCC-1; new CC chemokine 1; SCYA13; SCYL1; small inducible cytokine subfamily A (Cys-Cys), member 13; small-inducible cytokine A13
Common Name MCP-4
Gene Symbol CCL13
Biological Activity ED50 = 10-100 ng/mL; determined by the dose-dependent chemotaxis of human blood cells.
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Sequence Human CCL13 recombinant protein contains 75 amino acids
Content And Storage 4°C
Classification Carrier-Free
Activity ED50 = 10-100 ng/mL; determined by the dose-dependent chemotaxis of human blood cells.
Endotoxin Level <0.1 ng/μg
Shipping Condition Approved for shipment on Wet or Dry Ice
Expression System E. coli
Protein Family Chemokines & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype MCP⁄MCAF Chemokines
Research Category Signal Transduction, Immunology
Product Line Gibco
Purity or Quality Grade >98% by SDS-PAGE
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