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G-CSF Monoclonal Antibody (4A4RC), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

30070.00 NOK - 150400.00 NOK

Specifications

Antigen G-CSF
Clone 4A4RC
Concentration 1 mg/mL
Applications Functional Assay, Neutralization
Classification Monoclonal
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17101542
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Affymetrix eBioscience
16-7338-38
5 mg This item is currently unavailable or has been discontinued.
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17181532
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Affymetrix eBioscience
16-7338-025
25 mg This item is currently unavailable or has been discontinued.
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17191532
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Affymetrix eBioscience
16-7338-050
50 mg This item is currently unavailable or has been discontinued.
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Description

Description

This 4A4RC MAb reacts with G-CSF (Granulocyte Colony-Stimulating Factor), a growth factor that stimulates the proliferation, differentiation, and mobilization of hematopoetic stem cells. It is expressed by monocytes, macrophages, and bone marrow stromal cells, and can also be induced in fibroblasts by IL-17A. Unlike GM-CSF and IL-3, which can stimulate cells of multiple lineages, G-CSF activity is limited to neutrophilic granulocytes. G-CSF is essential to the maintenance of neutrophil counts during homeostasis, and low basal levels of the protein are detectable in the serum of healthy individuals. Circulating levels become elevated rapidly upon infection, as G-CSF is also important for the activation and mobilization of mature neutrophils during the innate immune response. G-CSF therapy is commonly used to treat neutropenia following bone marrow transplant or chemotherapy.

G-CSF Monoclonal antibody specifically detects G-CSF in Human samples. It is validated for Functional Assay, Neutralization
Specifications

Specifications

G-CSF
1 mg/mL
Monoclonal
Liquid
RUO
PBS with no preservative; pH 7.2
C17orf33; colony stimulating factor 3; colony stimulating factor 3 (granulocyte); CSF 3; Csf3; CSF3OS; Csfg; Filgrastim; GCSF; G-CSF; Granulocyte colony-stimulating factor; granulocyte-colony stimulating factor; gsf3; lenograstim; MGC45931; MGI-IG; Pluripoietin; RP23-395E10.4
IgG1 κ
Affinity chromatography
Antibody
4A4RC
Functional Assay, Neutralization
Functional Grade
Mouse
Human
P09919
1440
Primary
4° C
Csf3
Videos
SDS
Documents

Documents

Product Certifications