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Human FRAP1 (mTOR), GST Tag Recombinant Protein
Human FRAP1 (mTOR), GST Tag Recombinant Protein
Brand: Invitrogen PV4753
This item is not returnable.
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Description
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.Specifications
NP_004949.1 | |
163.9 kDa | |
FRAP1 (mTOR) | |
aa 1360-2549 | |
Recombinant | |
Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
|
Ser⁄Thr Kinases: Atypical | |
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™ | |
FK506 binding protein 12-rapamycin associated protein 1 | |
Kinases & Inhibitors | |
Liquid | |
Signal Transduction, Drug Development, Oncology |
Kinase Assay | |
10μg | |
PIKK Kinase Family | |
Human | |
GST Tag | |
Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic | |
Dry Ice | |
mTOR, FRAP1 | |
Baculovirus | |
Recombinant, Catalytic | |
Serine/Threonine Kinases |
For Research Use Only. Not for use in diagnostic procedures.