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FRAP1 (mTOR) Recombinant Human Protein

FRAP1 (mTOR) Recombinant Human Protein

Brand:  Invitrogen PV4753

Additional Details : Weight : 0.50000kg

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Product Code. 10012913

  • 7320.00 NOK / Each


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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
Specifications

Specifications

NP_004949.1
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
FRAP1 (mTOR) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
FRAP1 (mTOR) Recombinant Human Protein
Kinase assay
Baculovirus
Amino acids 1360-2549
34nmoles of phosphate transferred to PHAS-1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 5μg/mL
GST Tag
0.45mg/mL
163.9kDa
80% by SDS-PAGE
–80°C
1 Each
FRAP1 (mTOR)
FRAP1 (mTOR) was pre-diluted in enzyme dilution buffer and assayed in 50mM HEPES (pH 7.5), 10mM MnCl2, 1mM EGTA, 2.5mM DTT, 0.01% Polysorbate 20, 100μM ATP, 500μg/mL PHAS-1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
PIKK
FRAP1 (mTOR) Recombinant Human Protein
Human
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