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Fisogatinib, MedChemExpress

Product Code. 16485777
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Product Code. Quantity unitSize
16485777 5 mg 5mg
16479606 50 mg 50mg
16444346 100 mg 100mg
16413048 10 mg 10mg
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Product Code. 16485777

Brand: Medchem Express HY100492

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Description

MedChemExpress Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling.

Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling.

Specifications

Chemical Name or Material Fisogatinib
CAS 1707289-21-1
Color White
Purity Grade Notes Research
Molecular Formula C24H24Cl2N4O4
Quantity 5 mg
Synonym BLU-554
Solubility Information DMSO : 100 mg/mL (198.66 mM; Need ultrasonic)
SMILES C=CC(N[C@@H]1[C@H](NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2)COCC1)=O
Molecular Weight (g/mol) 503.38
Formula Weight 503.38
Percent Purity 98.82%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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