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Thermo Scientific Chemicals Finasteride, 98%

Product Code. 15492192 Shop All Thermo Scientific Chemicals Products
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Product Code. 15492192 Supplier Thermo Scientific Chemicals Supplier No. 458000050
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Description

Finasteride, CAS # 98319-26-7, is a 5α-reductase inhibitor that blocks conversion of testosterone and inhibits neurosteroid production.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Finasteride is an inhibitor of the enzyme 5α-reductase, which converts testosterone to dihydrotestosterone (DHT)
  • Finasteride also has been explored in neuroscience, as 5α-reductase enzymes are present in the central nervous system
  • Finasteride has been seen to cross the blood-brain barrier and block production of neurosteroids

Applications

  • Finasteride is mainly used in studies of prostate hyperplasia and tumors in mice, and can be studied in vitro or in vivo for its effects on hyperplasia, proliferation, and antioxidant activity
  • Its activity has also been explored in brain, liver and testis tissues
  • In vivo injection of finasteride has been shown to decrease neurogenesis and influence neuronal plasticity in mice
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 98319-26-7
Molecular Formula C23H36N2O2
Molecular Weight (g/mol) 372.54
InChI Key DBEPLOCGEIEOCV-WSBQPABSSA-N
Synonym finasteride, proscar, propecia, finastid, prostide, chibro-proscar, finasterida, finasteridum, finpecia, finasteridum inn-latin
PubChem CID 57363
ChEBI CHEBI:5062
IUPAC Name (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
SMILES CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C

Specifications

Melting Point 252.0°C to 254.0°C
Infrared Spectrum Authentic
Assay Percent Range 97.5% min. (HPLC)
Quantity 5 g
Solubility Information Solubility in water: very slightly soluble.
Formula Weight 372.54
Percent Purity 98%
Chemical Name or Material Finasteride

RUO – Research Use Only

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