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Description
FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.
Specifications
Specifications
| Antigen | FEM1A |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.13 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | FEM1A |
| Gene Accession No. | Q9BSK4 |
| Gene Alias | EPRAP, fem 1 homolog a (C. elegans), FEM1 alpha, FEM1A, Protein fem 1 homolog A |
| Gene Symbols | FEM1A |
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