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Fc Receptor Binding Inhibitor Polyclonal Antibody, Functional Grade, eBioscience™, Invitrogen™
Polyclonal Antibody
30070.00 NOK - 150400.00 NOK
Specifications
Antigen | Fc Receptor Binding Inhibitor |
---|---|
Concentration | 20 μL/Test |
Classification | Polyclonal |
Conjugate | Functional Grade |
Form | Liquid |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17121582
|
Affymetrix eBioscience
16-9161-38 |
5 mg |
30070.00 NOK
5mg |
Estimated Shipment: 30-05-2024 Log in to see stock. |
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17101582
|
Affymetrix eBioscience
16-9161-025 |
25 mg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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17111582
|
Affymetrix eBioscience
16-9161-050 |
50 mg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
The human FcgammaR-binding inhibitor can be used to inhibit the non-specific Fc-gamma receptor (FcgammaR)-mediated binding of mouse monoclonal antibodies used for flow cytometric analysis of human tissue. Four different classes of Fcgamma receptors have been identified: FcgammaRI (CD64), FcgammaRII (CD32), and FcgammaRIII (CD16), and they are expressed at varying levels in multiple cell lineages including high expression in myeloid, granulocyte and B cells. The biological function of the FcgammaR, including initiation of endocytosis, phagocytosis and antigen presentation, is elicited upon binding of host-immunoglobulin. The extent to which mouse monoclonal antibodies will bind to human FcgammaR varies depending on the isotype of the MAb. Furthermore, different monoclonal antibodies of the same isotype will display different binding to human FcgammaRs.
Four different classes of Fcy receptors have been identified: FcyRI (CD64), FcyRII (CD32), and FcyRIII (CD16), and they are expressed at varying levels in multiple cell lineages including high expression in myeloid, granulocyte and B cells. The biological function of the FcyR, including initiation of endocytosis, phagocytosis and antigen presentation, is elicited upon binding of host-immunoglobulin. The extent to which mouse monoclonal antibodies will bind to human FcyR varies depending on the isotype of the monoclonal antibody. Furthermore, different monoclonal antibodies of the same isotype will display different binding to human FcyRs.Specifications
Fc Receptor Binding Inhibitor | |
Polyclonal | |
Liquid | |
Human | |
Fc blocking; FcR BI; FcR Inhibitor | |
Affinity chromatography | |
Antibody |
20 μL/Test | |
Functional Grade | |
RUO | |
PBS with no preservative; pH 7.2 | |
Primary | |
4° C |