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Invitrogen™ Factor VII Polyclonal Antibody
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Product Code. 17227973 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
Product Code. Quantity unitSize
17227973 100 μL 100µL
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Product Code. 17227973

Brand: Invitrogen™ PA5115207

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This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Factor VII.

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Factor VII
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene F7
Gene Accession No. P08709, P70375, Q8K3U6
Gene Alias AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
Gene Symbols F7
Host Species Rabbit
Immunogen A synthesized peptide derived from human F7(Accession P08709), corresponding to amino acid residues C187-L237.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14068, 2155, 260320
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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