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Ethyl potassium malonate, 98%
Descripción
Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig's base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig′s base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.
Solubility
Soluble in water.
Notes
Hygroscopic. Incompatible with strong oxidizing agents.
Especificaciones
Especificaciones
| Melting Point | ∼200°C (decomposition) |
| pH | 9.1 |
| Odor | Odorless |
| Linear Formula | KO2CCH2CO2CH2CH3 |
| Quantity | 25 g |
| Beilstein | 3721682 |
| Sensitivity | Hygroscopic |
| Solubility Information | Soluble in water. |
| Formula Weight | 170.21 |
| Percent Purity | 98% |
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Seguridad y manipulación
- Ethyl potassium malonate
- Warning
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- MIXTURE LIST-Contain: Potassium ethyl malonate
RUO – Research Use Only
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