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Invitrogen™ EOMES Monoclonal Antibody (WD1928), Alexa Fluor™ 660, eBioscience™, Invitrogen™

Product Code. 17196238
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Quantity:
100 Tests
25 Tests
Unit Size:
Pack of 100
Pack of 25
Product Code. Quantity unitSize
17196238 25 Tests Pack of 25
17106248 100 Tests Pack of 100
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Product Code. 17196238

Brand: Invitrogen™ 606487741

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This item is not returnable. View return policy

Mouse Monoclonal Antibody

The WD1928 antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2). Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates. In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells. Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R.

TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EOMES
Applications Flow Cytometry
Classification Monoclonal
Clone WD1928
Concentration 5 μL/Test
Conjugate Alexa Fluor 660
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Eomes
Gene Accession No. O95936
Gene Alias C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Gene Symbols Eomes
Host Species Mouse
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100622125, 8320
Target Species Human, Pig
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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