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  6. EIF4B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

EIF4B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16847924 Shop All Proteintech Products
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150 μL
20 μL
Unit Size:
150µL
20µL
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16847924 150 μL 150µL
16857924 20 μL 20µL
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Product Code. 16847924 Supplier Proteintech Supplier No. 179171AP150UL

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Description

Rabbit Polyclonal Antibody

eIF4B is a multidomain eukaryotic translation initiation factor with a range of activities. It contains one RRM (RNA recognition) domain, a consensus RNA-binding site (RNP-CS) near the N terminus, and a central domain rich in aspartic acid, arginine, tyrosine, and glycine (DRYG). The DRYG domain of eIF4B helps in self-association and interaction with the p170 subunit of eIF3. eIF4B binds to both mRNA and 18S ribosomal RNA and thus acts as a bridge between the mRNA and the 40S ribosomal subunit during translation initiation. The ATPase and RNA helicase activity of the DEAD box protein eIF4A is stimulated by eIF4B and thus functions in close association with eIF4F a heterotrimeric protein that binds to mRNA cap structure and unwinds inhibitory secondary structure in the 5′ untranslated region of eucaryotic mRNAs in an ATP-dependent manner. Ubiquitous expression is seen in most of the tissues.

Specifications

Antigen EIF4B
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EIF4B
Gene Accession No. P23588, Q8BGD9
Gene Alias EIF 4B, EIF4B, PRO1843
Gene Symbols Eif4b
Host Species Rabbit
Immunogen EIF4B Fusion Protein Ag12325
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1975, 300253, 75705
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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