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EIF4B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1710.33 NOK - 4836.10 NOK

Specifications

Antigen EIF4B
Concentration 0.45 mg/mL
Applications Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16857924
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Proteintech
17917-1-AP-20UL
20 μL
1710.33 NOK
20µL
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16847924
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Proteintech
17917-1-AP-150UL
150 μL
4836.10 NOK
150µL
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Description

Description

eIF4B is a multidomain eukaryotic translation initiation factor with a range of activities. It contains one RRM (RNA recognition) domain, a consensus RNA-binding site (RNP-CS) near the N terminus, and a central domain rich in aspartic acid, arginine, tyrosine, and glycine (DRYG). The DRYG domain of eIF4B helps in self-association and interaction with the p170 subunit of eIF3. eIF4B binds to both mRNA and 18S ribosomal RNA and thus acts as a bridge between the mRNA and the 40S ribosomal subunit during translation initiation. The ATPase and RNA helicase activity of the DEAD box protein eIF4A is stimulated by eIF4B and thus functions in close association with eIF4F a heterotrimeric protein that binds to mRNA cap structure and unwinds inhibitory secondary structure in the 5′ untranslated region of eucaryotic mRNAs in an ATP-dependent manner. Ubiquitous expression is seen in most of the tissues.
Specifications

Specifications

EIF4B
Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
Unconjugated
Rabbit
Rat, Mouse, Human
P23588, Q8BGD9
1975, 300253, 75705
EIF4B Fusion Protein Ag12325
Primary
-20°C
EIF4B
0.45 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
EIF 4B, EIF4B, PRO1843
Eif4b
IgG
Antigen Affinity Chromatography
Antibody
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Documents

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