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  6. EHT 1864, MedChemExpress

EHT 1864, MedChemExpress

Product Code. 16479647
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
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50mg
5mg
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Product Code. 16479647

Brand: Medchem Express HY16659

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Description

MedChemExpress EHT 1864 is an inhibitor of Rac family small GTPases.

EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The Kd values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 also potently inhibits other Rac-dependent transformation processes, Tiam1- and Ras-mediated growth transformation. EHT 1864 prevents Aβ 40 and Aβ 42 production in vivo.

Specifications

Chemical Name or Material EHT 1864
Physical Form Powder
CAS 754240-09-0
Color Off-White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C25H29Cl2F3N2O4S
For Use With (Application) Cancer-Kinase/protease
Solubility Information H2O : ≥ 100 mg/mL (171.97 mM) ∣DMSO : ≥ 32 mg/mL (55.03 mM)
SMILES O=C1C=C(CN2CCOCC2)OC=C1OCCCCCSC3=CC=NC4=CC(C(F)(F)F)=CC=C34.[H]Cl.[H]Cl
Molecular Weight (g/mol) 581.48
Formula Weight 581.48
Percent Purity 99.7%
Grade Research
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Research purposes only

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