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EFHD2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12181-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.Specifications
| EFHD2 | |
| Polyclonal | |
| Unconjugated | |
| EFHD2 | |
| EFHD2, Swiprosin 1, SWS1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 27984, 79180 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin) | |
| 0.18 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q96C19, Q9D8Y0 | |
| Efhd2 | |
| EFHD2 Fusion Protein Ag2826 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |