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EFHD2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12181-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16899733

  • 1611.84 NOK / 20µL
Estimated Shipment: 14-03-2024
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Description

Description

EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.
Specifications

Specifications

EFHD2
Polyclonal
Unconjugated
EFHD2
EFHD2, Swiprosin 1, SWS1
Rabbit
Antigen Affinity Chromatography
RUO
27984, 79180
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.18 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q96C19, Q9D8Y0
Efhd2
EFHD2 Fusion Protein Ag2826
20 μL
Primary
Mouse, Human
Antibody
IgG
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