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EAI045, MedChemExpress

Product Code. 16474256
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Quantity:
50 mg
100 mg
Unit Size:
100mg
50mg
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Product Code. 16474256

Brand: Medchem Express HY100213

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Description

MedChemExpress EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.

EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.

Specifications

Chemical Name or Material EAI045
CAS 1942114-09-1
Color off White
Purity Grade Notes Research
Molecular Formula C19H14FN3O3S
Quantity 100 mg
Solubility Information DMSO : 100 mg/mL (260.82 mM; Need ultrasonic)
SMILES O=C(C(C1=C(O)C=CC(F)=C1)N2C(C(C=CC=C3)=C3C2)=O)NC4=NC=CS4
Molecular Weight (g/mol) 383.4
Formula Weight 383.4
Percent Purity 96.53%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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