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DTX3L Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11963-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.Specifications
| DTX3L | |
| Polyclonal | |
| Unconjugated | |
| DTX3L | |
| BBAP, deltex 3 like (Drosophila), DTX3L, Protein deltex 3 like, Rhysin 2, Rhysin2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 151636 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8TDB6 | |
| DTX3L | |
| DTX3L Fusion Protein Ag2568 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |