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DTX3L Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11963-1-AP-150UL

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Product Code. 16849383

  • 4836.10 NOK / 150µL

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Description

Description

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
Specifications

Specifications

DTX3L
Polyclonal
Unconjugated
DTX3L
BBAP, deltex 3 like (Drosophila), DTX3L, Protein deltex 3 like, Rhysin 2, Rhysin2
Rabbit
Antigen Affinity Chromatography
RUO
151636
-20°C
Liquid
Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8TDB6
DTX3L
DTX3L Fusion Protein Ag2568
150 μL
Primary
Human
Antibody
IgG
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