missing translation for 'onlineSavingsMsg'
Learn More
Learn More
DIO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11790-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3′,5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD). Alternative splicing results in multiple transcript variants encoding different isoforms. Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3′ UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Additional transcript variants have been described but are not supported by experimental evidence.Specifications
DIO1 | |
Polyclonal | |
Unconjugated | |
DIO1 | |
5DI, DIO1, DIOI, ITDI1, TXDI1, Type 1 DI, Type I 5 deiodinase | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
13370, 1733, 25430 | |
-20°C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.45 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P24389, P49895, Q61153 | |
DIO1 | |
DIO1 Fusion Protein Ag2410 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |