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DCX Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16862354 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16862354 150 μL 150µL
16872354 20 μL 20µL
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Product Code. 16862354

Brand: Proteintech 139251AP150UL

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Description

Rabbit Polyclonal Antibody

Anti-DCX antibodies are widely used for detection of neurogenesis. It is also a common neuron marker since its expression is specific to neurons.

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

Specifications

Antigen DCX
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DCX
Gene Accession No. O43602, O88809
Gene Alias DBCN, DC, DCX, doublecortin, Doublin, Lis X, Lissencephalin X, LISX, SCLH, XLIS
Gene Symbols DCX
Host Species Rabbit
Immunogen DCX Fusion Protein Ag4945
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13193, 1641
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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