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Darunavir, MedChemExpress

Product Code. 16489797
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Product Code. 16489797 Supplier Medchem Express Supplier No. HY17040

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Description

MedChemExpress Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 μM; IC90 = 0.009 μM) with minimal cytotoxicity.

Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 μM

Specifications

Chemical Name or Material Darunavir
Physical Form Solid
CAS 206361-99-1
Color White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C27H37N3O7S
For Use With (Application) COVID-19-anti-virus
Synonym TMC114 UIC-94017
Solubility Information DMSO : ≥ 100 mg/mL (182.60 mM)
SMILES O=C(O[C@@H]1[C@@]2([H])[C@@](OCC2)([H])OC1)N[C@@H](CC3=CC=CC=C3)[C@H](O)CN(S(=O)(C4=CC=C(N)C=C4)=O)CC(C)C
Molecular Weight (g/mol) 547.66
Formula Weight 547.66
Percent Purity 99.84%
Grade Research
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