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TOKU-E™ Daptomycin ReadyMade™ Solution

Product Code. 30044059
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Quantity:
10 x 0.5 mL
Unit Size:
5mL
Product Code. Quantity unitSize
30044059 10 x 0.5 mL 5mL
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Product Code. 30044059

Brand: TOKU-E™ D10810x0.5ML

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Description

Daptomycin ReadyMade™ Solution is provided as a sterile-filtered solution in ~ 10% β-cyclodextrin saline solution.

  • CAS Number: 103060-53-3
  • Molecular Formula: C72H101N17O26
  • Molecular Weight: 1620.67 g/mol
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Streptomyces roseosporus
  • Spectrum: Daptomycin targets Gram-positive organisms including GRE (glycopeptide-resistant Enterococci) and MRSA (methicillin-resistant Staphylococcus aureus)
  • Mechanism of Action: Daptomycin peptides interact with anionic phospholipids in the membrane of Gram-positive bacteria. Peptides integrate into the membrane by a calcium-mediated process and interact with membrane phospholipid head groups and acyl chains. Finally, a pore or channel is formed which can kill the cell by membrane disruption/depolarization or cellular uptake of Daptomycin leading to disruption of intracellular processes such as synthesis of DNA, RNA, and protein which results in bacterial cell death. The activity of Daptomycin is dependent on the presence of physiologic levels of free calcium ions

Specifications

Chemical Name or Material Daptomycin
Physical Form Liquid
CAS 103060-53-3
pH 6.5
Source Streptomyces roseosporus
Packaging 2 mL plastic vial
Sterile Filtered Yes, 0.22 μm
Sterility Sterile
Color Clear Colorless to Pale Yellow
Concentration 1 to 1.05 mg/mL
Quantity 10 x 0.5 mL
Purity Grade Notes >95% (HPLC)
Assay Percent Range >95.0%
Assay Percent Notes Daptomycin, Dried Basis
Molecular Formula C72H101N17O26
Product Line ReadyMade™ Solutions
Shipping Condition Ice Pack
Synonym LY-146032; Cubicin
IUPAC Name (3S)-3-[[(2R)-4-amino-2-[[(2S)-2-(decanoylamino)-3-(1H-indol-3-yl)propanoyl]amino]-4-oxobutanoyl]amino]-4-[[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonazacyclohentriacont-30-yl]amino]-4-oxobutanoic acid
Molecular Weight (g/mol) 1620.67 g/mol
Formula Weight 1620.67 amu
Percent Purity >95%
Grade Antibiotic
Concentration or Composition (by Analyte or Components) Daptomycin: 0.1%; Sulfobutyl Ether beta;-Cyclodextrin: 5 to 50%
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