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DAND5 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 22137-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.Specifications
DAND5 | |
Polyclonal | |
Unconjugated | |
DAND5 | |
CER2, Cerberus like protein 2, Cerl 2, CERL2, CKTSF1B3, COCO, CRL2, DAN domain family member 5, DAN domain family, member 5, DAND5, DANTE, GREM3, Gremlin 3, SP1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
199699 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.36 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q8N907 | |
DAND5 | |
DAND5 Fusion Protein Ag17533 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |