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DAND5 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 22137-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891665

  • 3468.15 NOK / 150µL
Estimated Shipment: 15-12-2022
to see stock.

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Description

Description

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
Specifications

Specifications

DAND5
Polyclonal
Unconjugated
DAND5
CER2, Cerberus like protein 2, Cerl 2, CERL2, CKTSF1B3, COCO, CRL2, DAN domain family member 5, DAN domain family, member 5, DAND5, DANTE, GREM3, Gremlin 3, SP1
Rabbit
Antigen Affinity Chromatography
RUO
199699
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N907
DAND5
DAND5 Fusion Protein Ag17533
150 μL
Primary
Human
Antibody
IgG
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