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  7. Dactolisib Tosylate, MedChemExpress

Dactolisib Tosylate, MedChemExpress

Product Code. p-200099451
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Product Code. 16481756 Supplier Medchem Express Supplier No. HY15174

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Description

MedChemExpress Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.

Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.

Specifications

Chemical Name or Material Dactolisib Tosylate
CAS 1028385-32-1
Color White
Purity Grade Notes Research
Molecular Formula C37H31N5O4S
Quantity 500 mg
Synonym BEZ235 TosylateNVP-BEZ 235 Tosylate
Solubility Information DMSO : 34 mg/mL (52.98 mM; Need ultrasonic and warming) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES CN(C1=C2C3=CC(C4=CC5=CC=CC=C5N=C4)=CC=C3N=C1)C(N2C6=CC=C(C=C6)C(C)(C#N)C)=O.CC7=CC=C(S(=O)(O)=O)C=C7
Molecular Weight (g/mol) 641.74
Formula Weight 641.74
Percent Purity 98.8%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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