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ACROBiosystems Cynomolgus DNAM-1 / CD226 Protein, His Tag
Brand: ACROBiosystems DN1-C52H9-1mg
Additional Details : Weight : 0.00010kg
Description
DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ∼65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.5 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| XP_005586537.1 | |
| 1 mg | |
| Glu 19 - Phe 252 | |
| DNAM1,CD226,PTA1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 28.5 kDa | |
| Cynomolgus DNAM-1, His Tag (DN1-C52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Phe 252 (Accession # A0A2K5W1Z6-1). | |
| -20°C | |
| DNAM-1 | |
| Cynomolgus Monkey | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |