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ACROBiosystems Cynomolgus DNAM-1 / CD226 Protein, His Tag

Brand:  ACROBiosystems DN1-C52H9-1mg

Additional Details : Weight : 0.00010kg

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Product Code. 16447469

  • 32169.11 NOK / 1mg
Estimated Shipment: 22-12-2022
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Description

Description

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ∼65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.5 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

XP_005586537.1
28.5 kDa
1 mg
Glu 19 - Phe 252
DNAM1,CD226,PTA1
Unconjugated
PBS, pH7.4
HEK293
Cynomolgus
Powder
>90% as determined by SDS-PAGE
Cynomolgus DNAM-1, His Tag (DN1-C52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Phe 252 (Accession # A0A2K5W1Z6-1).
-20°C
DNAM-1
His Tag
Less than 1.0 EU / µg by the LAL method.
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